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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
9.7
Human Site:
S1255
Identified Species:
16.41
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1255
V
E
A
R
P
P
L
S
P
E
R
A
P
E
H
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
E1110
S
P
V
T
P
L
P
E
Q
E
A
S
P
A
R
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
L44
L
P
T
A
P
P
S
L
P
H
L
P
E
F
E
Dog
Lupus familis
XP_543382
1925
209302
S1259
V
E
A
R
P
P
P
S
P
E
C
T
P
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1316
T
E
E
A
Q
L
P
S
P
P
E
H
G
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
D115
V
T
F
A
K
L
N
D
N
I
R
E
N
F
L
Chicken
Gallus gallus
Q5F3P8
2008
223067
T1324
E
E
D
R
L
P
R
T
P
G
R
E
V
V
V
Frog
Xenopus laevis
Q66J90
1938
216239
T1237
P
M
I
I
R
P
L
T
P
T
G
A
F
G
E
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
V1167
T
E
A
S
L
E
E
V
G
N
L
R
P
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
V1060
C
R
R
S
L
T
P
V
P
P
P
G
Y
N
E
Honey Bee
Apis mellifera
XP_395451
1406
159180
Q826
V
N
S
N
E
F
P
Q
C
D
D
E
A
S
P
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
K927
P
G
E
V
Q
R
R
K
T
S
V
L
S
N
D
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
S1205
V
E
S
K
A
F
K
S
F
E
T
W
W
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
L733
R
P
T
Q
R
V
D
L
R
S
L
H
H
R
L
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
20
20
73.3
N.A.
20
N.A.
N.A.
13.3
33.3
26.6
20
N.A.
6.6
6.6
0
26.6
P-Site Similarity:
100
26.6
26.6
73.3
N.A.
20
N.A.
N.A.
13.3
40
33.3
20
N.A.
6.6
20
0
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
22
8
0
0
0
0
0
8
15
8
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
8
0
8
8
0
0
8
15
% D
% Glu:
8
43
15
0
8
8
8
8
0
29
8
22
8
15
29
% E
% Phe:
0
0
8
0
0
15
0
0
8
0
0
0
8
15
0
% F
% Gly:
0
8
0
0
0
0
0
0
8
8
8
8
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
15
8
0
8
% H
% Ile:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
8
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
22
22
15
15
0
0
22
8
0
0
15
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
8
0
8
8
0
0
8
15
0
% N
% Pro:
15
22
0
0
29
36
36
0
50
15
8
8
29
15
8
% P
% Gln:
0
0
0
8
15
0
0
8
8
0
0
0
0
0
0
% Q
% Arg:
8
8
8
22
15
8
15
0
8
0
22
8
0
8
8
% R
% Ser:
8
0
15
15
0
0
8
29
0
15
0
8
8
8
0
% S
% Thr:
15
8
15
8
0
8
0
15
8
8
8
8
0
0
15
% T
% Val:
36
0
8
8
0
8
0
15
0
0
8
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _